الصفحة الرئيسية

كلية الصيدلة \ الصيدلانيات

سوسن أبو بكر أبو هاشم زيتون

نسبة اكتمال الملف الشخصي
الجنسية المصرية
التخصص العام علم السموم الصيدلية
التخصص الدقيق آليات عمل السموم
المسمى الوظيفي استاذ
الدرجة العلمية (المرتبة) دكتوراه

نبذه مختصرة

Dr Sawsan Zaitone received her Bachelor’s degree in Pharmaceutical Sciences in 2000 and her PhD in Medicines and Toxicology in 2007 • The doctor was promoted to the rank of associate professor in 2013 and then to the rank of professor in 2019 • The scientific production presented by Dr Sawsan Zaitone is represented in the number of 80 scientific papers published internationally in journals classified in Scopus and WOS databases • 32 research papers, including masters and doctoral theses, registered in different universities • These researches were carried out with the participation of 152 research associates from different scientific departments in the Egyptian faculties of pharmacy, such as the Department of Biochemistry, Pharmaceutical Chemistry, Pharmacognosy and pharmacies, as well as with the faculties of medicine, pharmacy, science, veterinary medicine and dentistry These researches were carried out with the participation of 152 research associates from different scientific departments in the Egyptian faculties of pharmacy, such as the Department of Biochemistry, Pharmaceutical Chemistry, Pharmacognosy and pharmacies, as well as with the faculties of medicine, pharmacy, science, veterinary medicine and dentistry • Participation was made with government universities such as Cairo, Ain Shams, Al-Azhar, Tanta University, Mansoura, Assiut and Zagazig in Egypt • Participation was made with private universities such as Sinai University, Future University and the Russian University in Egypt • Participation was made with prestigious Arab universities such as King Abdulaziz University and King Saud University, as well as the University of Tabuk and the University of Knowledge in Saudi Arabia • Research cooperation is underway with more Egyptian Arab universities • Dr Sawsan Zaitone supervised 24 masters theses and 4 doctoral theses in the field of pharmacology and toxicology at Suez Canal University • The doctor supervised a number of masters and doctoral theses at the Faculty of Pharmacy, Cairo University, Al-Azhar University, the Faculty of Dentistry, and the Faculty of Science, Suez Canal University • The doctor participated in the judging and discussion committees for 9 masters theses and 2 doctoral theses • Dr Sawsan participated as an arbitrator for research and awards in the conference of young researchers at Suez Canal University • Dr Sawsan is an international reviewer in the number of 81 international journals classified by WOS and Scopus • The doctor has participated in a number of local and international conferences, as well as with societal bodies • The doctor won the award for the best research presented at the Suez Canal Authority Conference on Cardiology in 2015 and 2016 • The doctor has been working at the Faculty of Pharmacy at Tabuk University since February 25, 2016 to date She participates in academic teaching, student field training, supervises graduation projects, and participates in multiple research groups to publish scientific research

المؤهلات العلمية

Bachelor degree in Pharmaceutical Sciences from Suez Canal University, Egypt 2000 Masters degree in Pharmaceutical Sciences from Suez Canal University, Egypt 2004 PhD degree in Pharmaceutical Sciences from Suez Canal University, Egypt 2007

الاهتمامات البحثية

Neuropharmacology Chemotherapy

الخبرات والمناصب الإدارية

Coordinator of the exam committee at the female section of Faculty of Pharmacy Member of the academic affairs unit at the Faculty of Pharmacy in University of Tabuk Member of the scientific research unit at the Faculty of Pharmacy in University of Tabuk Member of the electronic learning resources unit at the Faculty of Pharmacy in University of Tabuk

الجدول الدراسي
اليوم المادة الوقت
من إلى
الأحد Graduation project 08:00 12:00
الأحد Drug dependence and abuse PDPT0403 Lecture 10:00 12:00
الأحد Drug dependence and abuse PDPT0403 Tutorials 13:00 15:00
الإثنين Pharmaceutical field training 2 FT102 (girls) 08:00 16:00
الثلاثاء ACADEMIC ADVISING 10:00 12:00
الثلاثاء Office hours for Pharmacology 2 13:00 15:00
الأربعاء Pharmacology 2 Practical 10:00 12:00
الأربعاء Academic advising 13:00 15:00
الخميس Office hours drugs of abuse PDPT0403 10:00 12:00
الأبحاث والمؤلفات
  • El-Ghaiesh, S H, Bahr, H I, Ibrahiem, A T, Ghorab, D, Alomar, S Y, Farag, N E, & Zaitone, S A (2020) Metformin protects from rotenone–induced nigrostriatal neuronal death in adult mice by activating AMPK-FOXO3 signaling and mitigation of angiogenesis Frontiers in Molecular Neuroscience, 13, 84
  • Alzahrani, S, Zaitone, S A, Said, E, El-Sherbiny, M, Ajwah, S, Alsharif, S Y, & Elsherbiny, N M (2020) Protective effect of isoliquiritigenin on experimental diabetic nephropathy in rats: impact on Sirt-1/NFκB balance and NLRP3 expression International Immunopharmacology, 87, 106813‏
  • Bendary, M M, Ibrahim, D, Mosbah, R A, Mosallam, F, Hegazy, W A, Awad, N F, & Marwa, I (2021) Thymol nanoemulsion: A new therapeutic option for extensively drug resistant foodborne pathogens Antibiotics, 10(1), 25‏
  • Abdel-Sattar, E, Mahrous, E A, Thabet, M M, Elnaggar, D M Y, Youssef, A M, Elhawary, R, & Mekky, R H (2021) Methanolic extracts of a selected Egyptian Vicia faba cultivar mitigate the oxidative/inflammatory burden and afford neuroprotection in a mouse model of Parkinson’s disease Inflammopharmacology, 29(1), 221-235‏
  • El-Sherbeeny, N A, Soliman, N, Youssef, A M, Abd El-Fadeal, N M, El-Abaseri, T B, Hashish, A A, & Zaitone, S A (2020) The protective effect of biochanin A against rotenone-induced neurotoxicity in mice involves enhancing of PI3K/Akt/mTOR signaling and beclin-1 production Ecotoxicology and Environmental Safety, 205, 111344‏
  • Mohamed, M T, Zaitone, S A, Ahmed, A, Mehanna, E T, & El-Sayed, N M (2020) Raspberry ketones attenuate cyclophosphamide-induced pulmonary toxicity in mice through inhibition of oxidative stress and NF-ΚB pathway Antioxidants, 9(11), 1168‏
  • A Attia, M, Enan, E T, Hashish, A A, MH El-kannishy, S, Gardouh, A R, K Tawfik, M, & Zaitone, S A (2021) Chemopreventive Effect of 5-Flurouracil Polymeric Hybrid PLGA-Lecithin Nanoparticles against Colon Dysplasia Model in Mice and Impact on p53 Apoptosis Biomolecules, 11(1), 109‏
  • Alzahrani, S, Ajwah, S M, Alsharif, S Y, Said, E, El-Sherbiny, M, Zaitone, S A, & Elsherbiny, N M (2020) Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury Naunyn-Schmiedebergs Archives of Pharmacology, 393(12), 2375-2385‏
  • Saad, Z A, Khodeer, D M, Zaitone, S A, Ahmed, A A, & Moustafa, Y M (2020) Exenatide ameliorates experimental non-alcoholic fatty liver in rats via suppression of toll-like receptor 4/NFκB signaling: Comparison to metformin Life sciences, 253, 117725‏
  • Alomar, S Y, Barakat, B M, Eldosoky, M, Atef, H, Mohamed, A S, Elhawary, R, & Zaitone, S A (2021) Protective effect of metformin on rat diabetic retinopathy involves suppression of toll-like receptor 4/nuclear factor-k B expression and glutamate excitotoxicity International Immunopharmacology, 90, 107193‏
  • Zaitone, S A, Alshaman, R, Alattar, A, Elsherbiny, N M, Abogresha, N M, El-Kherbetawy, M K, & Ahmed, E (2020) Retinoprotective effect of donepezil in diabetic mice involves mitigation of excitotoxicity and activation of PI3K/mTOR/BCl2 pathway Life Sciences, 262, 118467‏
  • Zaitone, S A, Alshaman, R, Alattar, A, Elsherbiny, N M, Abogresha, N M, El-Kherbetawy, M K, & Ahmed, E (2020) Retinoprotective effect of donepezil in diabetic mice involves mitigation of excitotoxicity and activation of PI3K/mTOR/BCl2 pathway Life Sciences, 262, 118467‏
  • El-Sherbeeny, N A, Ibrahiem, A T, Ali, H S, Farag, N E, Toraih, E A, & Zaitone, S A (2020) Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1 5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia Archives of Pharmacal Research, 43(7), 724-734‏
  • Elsherbiny, N M, El-Sherbiny, M, & Zaitone, S A (2020) Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma: Role of Notch signaling Pathology-Research and Practice, 216(10), 153139‏
  • El-Sherbiny, M, Atef, H, Eladl, M A, Mohamed, A S, El-Shafey, M, Ali, H S, & Attia, M A (2021) Leflunomide induces dose-dependent lung injury in mice via stimulating vimentin and NLRP3 inflammasome production Frontiers in Pharmacology, 12, 649‏
  • Farag, N E, El-Kherbetawy, M K, Ismail, H M, Abdelrady, A M, Toraih, E A, Abdelbasset, W K, & Zaitone, S A (2021) Differential Effect of Three Macrolide Antibiotics on Cardiac Pathology and Electrophysiology in a Myocardial Infarction Rat Model: Influence on Sodium Nav1 5 Channel Expression Pharmaceuticals, 14(7), 597‏
  • Alomar, S Y, Gheit, R E, Enan, E T, El-Bayoumi, K S, Shoaeir, M Z, Elkazaz, A Y, & El-Sayed, R M (2021) Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis Pharmaceuticals, 14(4), 307‏
  • El-Fadeal, A, Noha, M, Nafie, M S, K El-kherbetawy, M, El-mistekawy, A, Mohammad, H M, & Zaitone, S A (2021) Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/β-Catenin Signaling Inhibition International Journal of Molecular Sciences, 22(10), 5213‏
  • Shaalan, A A, El-Sherbiny, M, El-Abaseri, T B, Shoaeir, M Z, Abdel-Aziz, T M, Mohamed, M I, & Mohammad, H M (2020) Supplement with calcium or alendronate suppresses osteopenia due to long term rabeprazole treatment in female mice: influence on bone TRAP and osteopontin levels Frontiers in Pharmacology, 11, 583‏
  • Gardouh, A R, Attia, M A, Enan, E T, Elbahaie, A M, Fouad, R A, El-Shafey, M, & Qushawy, M K (2020) Synthesis and antitumor activity of doxycycline polymeric nanoparticles: Effect on tumor apoptosis in solid ehrlich carcinoma Molecules, 25(14), 3230‏
  • Mohammad, H M, Makary, S, Atef, H, El-Sherbiny, M, Atteia, H H, Ibrahim, G A, & Zaitone, S A (2020) Clopidogrel or prasugrel reduces mortality and lessens cardiovascular damage from acute myocardial infarction in hypercholesterolemic male rats Life sciences, 247, 117429‏
  • Alzahrani, S, Said, E, Ajwah, S M, Alsharif, S Y, El-Bayoumi, K S, Zaitone, S A, & Elsherbiny, N M (2021) Isoliquiritigenin attenuates inflammation and modulates Nrf2/caspase-3 signalling in STZ-induced aortic injury Journal of Pharmacy and Pharmacology, 73(2), 193-205‏
  • Elsherbiny, N M, Said, E, Atef, H, & Zaitone, S A (2020) Renoprotective effect of calycosin in high fat diet-fed/STZ injected rats: Effect on IL-33/ST2 signaling, oxidative stress and fibrosis suppression Chemico-biological interactions, 315, 108897‏
  • Elsherbiny, N M, Said, E, Atef, H, & Zaitone, S A (2020) Renoprotective effect of calycosin in high fat diet-fed/STZ injected rats: Effect on IL-33/ST2 signaling, oxidative stress and fibrosis suppression Chemico-biological interactions, 315, 108897‏
  • Atteia, H H, Alzahrani, S, El-Sherbeeny, N A, Youssef, A M, Farag, N E, Mehanna, E T, & Zaitone, S A (2020) Evening primrose oil ameliorates hyperleptinemia and reproductive hormone disturbances in obese female rats: impact on estrus cyclicity Frontiers in endocrinology, 10, 942‏
  • Elshaer, R E, Elgammal, E R, Elmistekawy, A M, Ghannam, W A, Elshamy, A E, Abed, S Y, & Zaitone, S A (2021) Preoperative Diagnosis Failure for a Rare Gastric Collision Tumor: A Case Report Diagnostics, 11(4), 633‏
  • Abd Al Haleem, E N, Ibrahim, F, Zaitone, S A, & Arafa, H E D (2021) Possible Protective Effect of TNF-α Inhibition and Triad NO/cGMP/VEGF Activation on Gastric Ulcer in Rats Canadian Journal of Physiology and Pharmacology, (ja)‏
  • El-Mistekawy, A, Salama, A, & Alomar, S Y (2021) Chemopreventive Effect of 5-Flurouracil Polymeric Hybrid PLGA-Lecithin Nanoparticles against Colon Dysplasia Model in Mice and Impact on p53 Apoptosis Biomolecules 2021, 11, 109‏
جوائز التميز
  • (2020-2021) The award of distinguished staff member in scientific research in Faculty of Pharmacy in University of Tabuk at academic year 1442 H
  • Award of best applied research from the community service section (Prof Ahmed Askar Award) the most prestigious award in Suez Canal University in 2021
  • Award of best applied research from the higher studies and research section in Suez Canal University in 2021
  • The best moderated e-poster in the 3rd annual Cardiology Conference of Suez Canal Authority, held at Fairmont-Heliopolis Hotel, Cairo, Egypt [28th April 2016]
  • The best moderated e-poster in the 2nd annual Cardiology Conference of Suez Canal Authority in collaboration with the Egyptian Society of Cardiology, held at Intercontinental City Stars, Cairo, Egypt [23-24 April 2015]
  • One of the top 2% scientists in the world as announced by Stanford University in October 2021
  • Position number 4 in scientists working in Saudi Universities who peer reviews for WOS journals in 2021
  • Winner of the second place in the best poster presentation in SIPHA conference 2022 held in Riyadh, Saudi Arabia
  • Winner of the most cited article award (duration 2019-2021) in University of Tabuk
  • The Polymers 2021 Outstanding Reviewer Award
المشاريع البحثية
اسم المشروع وصف المشروع
Protective effect of Caffeic acid phenethyl ester against rotenone induced neurodegeneration: implication for Parkinson’s disease therapy Funded by the Deanship of Scientific Research in University of Tabuk
Modulation of peripheral neuropathy and spinal glia activity in diabetic mice by valproate sodium: possible histone deacetylase inhibition Funded by the DSR in University of Tabuk (code S-1439-0104)
Neuroprotective effect of donepezil against diabetic retinopathy and optic nerve damage: possible downregulation of glutamate receptors and modulation of AMPK/mTOR pathway Funded by the DSR in University of Tabuk
Therapeutic potential of of nanoemulsion preparations of natural oils in alleviating experimental insulin resistance and fatty liver diseases Funded by the DSR in University of Tabuk (code S-0083-1442)
معلومات التواصل
البريد الإلكتروني : szaitone@ut.edu.sa
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